Claude Opus 4.5 vs Nova Pro on Amazon Bedrock

In us-east-1, Nova Pro costs $0.800 per 1M input tokens against $5.00 — a 6.3× difference. Prices, context, capabilities and region coverage below.

anthropic.claude-opus-4-5-20251101-v1:0
Input / 1M
$5.00
Output / 1M
$25.00
Context
200K
Est. / month
$5,850
Nova Pro Amazon
amazon.nova-pro-v1:0
Input / 1M
$0.800
Output / 1M
$3.20
Context
300K
Est. / month
$864.00

Capabilities

Capability Claude Opus 4.5 Nova Pro
Tool use
Vision
Prompt caching
Batch inference
Streaming

Region availability

Region Claude Opus 4.5 Nova Pro
us-east-1 US East (N. Virginia) Inference profile only On-demand
us-east-2 US East (Ohio) Inference profile only Inference profile only
us-west-2 US West (Oregon) Inference profile only Inference profile only
ca-central-1 Canada (Central) Inference profile only Not available
eu-west-1 EU (Ireland) Inference profile only Inference profile only
eu-west-2 EU (London) Inference profile only On-demand
eu-west-3 EU (Paris) Inference profile only Inference profile only
eu-central-1 EU (Frankfurt) Inference profile only Inference profile only
eu-north-1 EU (Stockholm) Inference profile only Inference profile only
ap-southeast-1 Asia Pacific (Singapore) Inference profile only Inference profile only
ap-southeast-2 Asia Pacific (Sydney) Inference profile only On-demand
ap-northeast-1 Asia Pacific (Tokyo) Inference profile only Inference profile only
ap-northeast-2 Asia Pacific (Seoul) Inference profile only Inference profile only
ap-northeast-3 Asia Pacific (Osaka) Inference profile only Not available
ap-south-1 Asia Pacific (Mumbai) Inference profile only Inference profile only
sa-east-1 South America (Sao Paulo) Inference profile only Not available

13 of 16 regions support both models.

Common questions

Is Claude Opus 4.5 or Nova Pro cheaper on Amazon Bedrock?
Nova Pro is cheaper on input tokens: $0.800 against $5.00 per 1M in us-east-1, a 6.3× difference. At 2,000 runs a day with 12,000 input and 1,500 output tokens each, that is $864.00 against $5,850 a month before any caching or batch discount.
Does Claude Opus 4.5 or Nova Pro have the larger context window?
Nova Pro, at 300K tokens against 200K.
Which regions support Claude Opus 4.5 and Nova Pro?
Claude Opus 4.5 runs in 16 of the 16 AWS regions tracked here and Nova Pro in 13. 13 regions support both, so a workload that may switch between them should target one of those.